This issue happened with windows update or if the particular excel file is new to computer. When troubleshooting this kind of a issue. We have consider few more things. As this might be happened due to an another issue. below steps will help you to determine the issue and resolve in perfect manner.
1. Make sure MS office is running with the latest updates.
2. Make sure macros not disabled from the options.
If those are clear most probably problem is with the system detect this file as unsafe. To sort this one out right click the file and choose the unblock check mark. This should resolve the issue.
